node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADL58292.1 | fno | MTBMA_c06970 | MTBMA_c06980 | Predicted sugar phosphate isomerase / epimerase. | F420H2:NADP oxidoreductase; Catalyzes the reduction of NADP(+) with F420H(2) via hydride transfer, and the reverse reaction, i.e. the reduction of F420 with NADPH. Probably functions in the regeneration of NADPH required in biosynthetic reactions; Belongs to the F420-dependent NADP reductase family. | 0.799 |
ADL58292.1 | phi2 | MTBMA_c06970 | MTBMA_c06990 | Predicted sugar phosphate isomerase / epimerase. | Predicted 3-hexulose-6-phosphate isomerase. | 0.750 |
cofD | cofE | MTBMA_c14000 | MTBMA_c14010 | LPPG:FO 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. | F420-0:gamma-glutamyl ligase; Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8- didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420- 0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives. | 0.999 |
cofD | fno | MTBMA_c14000 | MTBMA_c06980 | LPPG:FO 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. | F420H2:NADP oxidoreductase; Catalyzes the reduction of NADP(+) with F420H(2) via hydride transfer, and the reverse reaction, i.e. the reduction of F420 with NADPH. Probably functions in the regeneration of NADPH required in biosynthetic reactions; Belongs to the F420-dependent NADP reductase family. | 0.779 |
cofD | mer | MTBMA_c14000 | MTBMA_c03270 | LPPG:FO 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. | F420-dependent methylenetetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family. | 0.844 |
cofE | cofD | MTBMA_c14010 | MTBMA_c14000 | F420-0:gamma-glutamyl ligase; Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8- didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420- 0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives. | LPPG:FO 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. | 0.999 |
cofE | fno | MTBMA_c14010 | MTBMA_c06980 | F420-0:gamma-glutamyl ligase; Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8- didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420- 0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives. | F420H2:NADP oxidoreductase; Catalyzes the reduction of NADP(+) with F420H(2) via hydride transfer, and the reverse reaction, i.e. the reduction of F420 with NADPH. Probably functions in the regeneration of NADPH required in biosynthetic reactions; Belongs to the F420-dependent NADP reductase family. | 0.794 |
cofE | mer | MTBMA_c14010 | MTBMA_c03270 | F420-0:gamma-glutamyl ligase; Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8- didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420- 0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives. | F420-dependent methylenetetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family. | 0.838 |
fno | ADL58292.1 | MTBMA_c06980 | MTBMA_c06970 | F420H2:NADP oxidoreductase; Catalyzes the reduction of NADP(+) with F420H(2) via hydride transfer, and the reverse reaction, i.e. the reduction of F420 with NADPH. Probably functions in the regeneration of NADPH required in biosynthetic reactions; Belongs to the F420-dependent NADP reductase family. | Predicted sugar phosphate isomerase / epimerase. | 0.799 |
fno | cofD | MTBMA_c06980 | MTBMA_c14000 | F420H2:NADP oxidoreductase; Catalyzes the reduction of NADP(+) with F420H(2) via hydride transfer, and the reverse reaction, i.e. the reduction of F420 with NADPH. Probably functions in the regeneration of NADPH required in biosynthetic reactions; Belongs to the F420-dependent NADP reductase family. | LPPG:FO 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. | 0.779 |
fno | cofE | MTBMA_c06980 | MTBMA_c14010 | F420H2:NADP oxidoreductase; Catalyzes the reduction of NADP(+) with F420H(2) via hydride transfer, and the reverse reaction, i.e. the reduction of F420 with NADPH. Probably functions in the regeneration of NADPH required in biosynthetic reactions; Belongs to the F420-dependent NADP reductase family. | F420-0:gamma-glutamyl ligase; Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8- didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420- 0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives. | 0.794 |
fno | frhB | MTBMA_c06980 | MTBMA_c16830 | F420H2:NADP oxidoreductase; Catalyzes the reduction of NADP(+) with F420H(2) via hydride transfer, and the reverse reaction, i.e. the reduction of F420 with NADPH. Probably functions in the regeneration of NADPH required in biosynthetic reactions; Belongs to the F420-dependent NADP reductase family. | F420-reducing hydrogenase, subunit beta. | 0.814 |
fno | hdrB | MTBMA_c06980 | MTBMA_c04500 | F420H2:NADP oxidoreductase; Catalyzes the reduction of NADP(+) with F420H(2) via hydride transfer, and the reverse reaction, i.e. the reduction of F420 with NADPH. Probably functions in the regeneration of NADPH required in biosynthetic reactions; Belongs to the F420-dependent NADP reductase family. | CoB-CoM heterodisulfide reductase, subunit B; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B); Belongs to the HdrB family. | 0.768 |
fno | mer | MTBMA_c06980 | MTBMA_c03270 | F420H2:NADP oxidoreductase; Catalyzes the reduction of NADP(+) with F420H(2) via hydride transfer, and the reverse reaction, i.e. the reduction of F420 with NADPH. Probably functions in the regeneration of NADPH required in biosynthetic reactions; Belongs to the F420-dependent NADP reductase family. | F420-dependent methylenetetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family. | 0.855 |
fno | mvhG | MTBMA_c06980 | MTBMA_c15180 | F420H2:NADP oxidoreductase; Catalyzes the reduction of NADP(+) with F420H(2) via hydride transfer, and the reverse reaction, i.e. the reduction of F420 with NADPH. Probably functions in the regeneration of NADPH required in biosynthetic reactions; Belongs to the F420-dependent NADP reductase family. | F420-non-reducing hydrogenase, subunit G; Part of a complex that provides reducing equivalents for heterodisulfide reductase; Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family. | 0.806 |
fno | nifE | MTBMA_c06980 | MTBMA_c01510 | F420H2:NADP oxidoreductase; Catalyzes the reduction of NADP(+) with F420H(2) via hydride transfer, and the reverse reaction, i.e. the reduction of F420 with NADPH. Probably functions in the regeneration of NADPH required in biosynthetic reactions; Belongs to the F420-dependent NADP reductase family. | Nitrogenase iron-molybdenum cofactor biosynthesis protein NifE; This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor); Belongs to the NifD/NifK/NifE/NifN family. | 0.781 |
fno | nifH1 | MTBMA_c06980 | MTBMA_c01460 | F420H2:NADP oxidoreductase; Catalyzes the reduction of NADP(+) with F420H(2) via hydride transfer, and the reverse reaction, i.e. the reduction of F420 with NADPH. Probably functions in the regeneration of NADPH required in biosynthetic reactions; Belongs to the F420-dependent NADP reductase family. | Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein. | 0.791 |
fno | phi2 | MTBMA_c06980 | MTBMA_c06990 | F420H2:NADP oxidoreductase; Catalyzes the reduction of NADP(+) with F420H(2) via hydride transfer, and the reverse reaction, i.e. the reduction of F420 with NADPH. Probably functions in the regeneration of NADPH required in biosynthetic reactions; Belongs to the F420-dependent NADP reductase family. | Predicted 3-hexulose-6-phosphate isomerase. | 0.805 |
frhB | fno | MTBMA_c16830 | MTBMA_c06980 | F420-reducing hydrogenase, subunit beta. | F420H2:NADP oxidoreductase; Catalyzes the reduction of NADP(+) with F420H(2) via hydride transfer, and the reverse reaction, i.e. the reduction of F420 with NADPH. Probably functions in the regeneration of NADPH required in biosynthetic reactions; Belongs to the F420-dependent NADP reductase family. | 0.814 |
frhB | hdrB | MTBMA_c16830 | MTBMA_c04500 | F420-reducing hydrogenase, subunit beta. | CoB-CoM heterodisulfide reductase, subunit B; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B); Belongs to the HdrB family. | 0.889 |