| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADL58431.1 | asnB | MTBMA_c08360 | MTBMA_c08090 | Predicted sensory transduction regulatory protein. | Asparagine synthase; Glutamine-hydrolyzing. | 0.546 |
| ADL58431.1 | uvrB | MTBMA_c08360 | MTBMA_c08380 | Predicted sensory transduction regulatory protein. | Excinuclease ABC, subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.526 |
| ADL58431.1 | uvrC | MTBMA_c08360 | MTBMA_c08370 | Predicted sensory transduction regulatory protein. | Excinuclease ABC, subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.724 |
| ADL58478.1 | uvrC | MTBMA_c08830 | MTBMA_c08370 | Conserved hypothetical protein. | Excinuclease ABC, subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.999 |
| asnB | ADL58431.1 | MTBMA_c08090 | MTBMA_c08360 | Asparagine synthase; Glutamine-hydrolyzing. | Predicted sensory transduction regulatory protein. | 0.546 |
| asnB | lysC | MTBMA_c08090 | MTBMA_c11980 | Asparagine synthase; Glutamine-hydrolyzing. | Aspartate kinase; Belongs to the aspartokinase family. | 0.986 |
| asnB | nth | MTBMA_c08090 | MTBMA_c11590 | Asparagine synthase; Glutamine-hydrolyzing. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.491 |
| asnB | uvrA | MTBMA_c08090 | MTBMA_c08390 | Asparagine synthase; Glutamine-hydrolyzing. | Excinuclease ABC, subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.507 |
| asnB | uvrC | MTBMA_c08090 | MTBMA_c08370 | Asparagine synthase; Glutamine-hydrolyzing. | Excinuclease ABC, subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.646 |
| lysC | asnB | MTBMA_c11980 | MTBMA_c08090 | Aspartate kinase; Belongs to the aspartokinase family. | Asparagine synthase; Glutamine-hydrolyzing. | 0.986 |
| lysC | mutS | MTBMA_c11980 | MTBMA_c03390 | Aspartate kinase; Belongs to the aspartokinase family. | Predicted DNA mismatch recognition protein MutS; Has ATPase and non-specific DNA-binding activities. Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily. | 0.437 |
| lysC | uvrC | MTBMA_c11980 | MTBMA_c08370 | Aspartate kinase; Belongs to the aspartokinase family. | Excinuclease ABC, subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.793 |
| mutS | lysC | MTBMA_c03390 | MTBMA_c11980 | Predicted DNA mismatch recognition protein MutS; Has ATPase and non-specific DNA-binding activities. Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily. | Aspartate kinase; Belongs to the aspartokinase family. | 0.437 |
| mutS | uvrB | MTBMA_c03390 | MTBMA_c08380 | Predicted DNA mismatch recognition protein MutS; Has ATPase and non-specific DNA-binding activities. Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily. | Excinuclease ABC, subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.444 |
| mutS | uvrC | MTBMA_c03390 | MTBMA_c08370 | Predicted DNA mismatch recognition protein MutS; Has ATPase and non-specific DNA-binding activities. Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily. | Excinuclease ABC, subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.620 |
| nth | asnB | MTBMA_c11590 | MTBMA_c08090 | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | Asparagine synthase; Glutamine-hydrolyzing. | 0.491 |
| nth | uvrA | MTBMA_c11590 | MTBMA_c08390 | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | Excinuclease ABC, subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.417 |
| nth | uvrB | MTBMA_c11590 | MTBMA_c08380 | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | Excinuclease ABC, subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.488 |
| nth | uvrC | MTBMA_c11590 | MTBMA_c08370 | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | Excinuclease ABC, subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.737 |
| pcrA1 | pcrA2 | MTBMA_c08650 | MTBMA_c09010 | ATP-dependent DNA helicase. | ATP-dependent DNA helicase. | 0.917 |
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