STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nikR2Predicted nickel responsive regulator. (127 aa)    
Predicted Functional Partners:
ADL58580.1
Predicted Mn2+/Zn2+ ABC transporter, ATPase component.
     
 0.650
ADL58581.1
Predicted Mn2+/Zn2+ ABC transporter, permease component.
     
 0.643
ADL58579.1
Predicted extracellular metal-binding protein.
     
 0.606
mptA
Conserved hypothetical protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
 
   
 0.530
purP
Predicted 5-formaminoimidazole-4-carboxamide-1-(beta)-D- ribofuranosyl 5'- monophosphate synthetase; Catalyzes the ATP- and formate-dependent formylation of 5- aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates.
  
   
 0.523
tfx
DNA-binding protein; Transcriptional activator of the fmdECB operon.
 
   
 0.482
mfnA
L-tyrosine decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily.
     
 0.418
carB
Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family.
     
 0.415
ADL58248.1
5-formyltetrahydrofolate cyclo-ligase-related protein.
     
 0.412
ADL58582.1
Conserved hypothetical protein.
       0.412
Your Current Organism:
Methanothermobacter marburgensis
NCBI taxonomy Id: 79929
Other names: M. marburgensis str. Marburg, Methanobacterium thermoautotrophicum (strain Marburg / DSM 2133), Methanobacterium thermoautotrophicum str. Marburg, Methanothermobacter marburgensis str. Marburg, Methanothermobacter marburgensis strain Marburg
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