STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADL58659.1Conserved hypothetical protein. (92 aa)    
Predicted Functional Partners:
ADL58661.1
Predicted DNA-directed RNA polymerase II, subunit RPC10.
  
    0.948
ADL58660.1
Imp4-like protein; Probably involved in the biogenesis of the ribosome.
  
    0.938
pfdB
Prefoldin, beta subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
  
    0.908
rpl37ae
50S ribosomal protein L37Ae; Binds to the 23S rRNA.
       0.847
ADL58657.1
Conserved hypothetical protein.
       0.816
rpr41
Predicted exosome RNA binding protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.
       0.643
rpr42
Predicted exosome RNA binding protein; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.
       0.643
rpr43
Predicted exosome RNA binding protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.
       0.619
ADL58666.1
Predicted exosome subunit.
       0.575
psmA
Predicted proteasome, subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
       0.575
Your Current Organism:
Methanothermobacter marburgensis
NCBI taxonomy Id: 79929
Other names: M. marburgensis str. Marburg, Methanobacterium thermoautotrophicum (strain Marburg / DSM 2133), Methanobacterium thermoautotrophicum str. Marburg, Methanothermobacter marburgensis str. Marburg, Methanothermobacter marburgensis strain Marburg
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