Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
speBPredicted arginase/agmatinase/formimionoglutamate hydrolase; Belongs to the arginase family. (287 aa)    
Predicted Functional Partners:
pdaD
Predicted pyruvoyl-dependent arginine decarboxylase; Belongs to the PdaD family.
 
  
 0.970
eif5A
Translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
 
  
 0.929
ADL58950.1
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.847
leuS
leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
 
 0.780
valS
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
  
  
 0.776
argD
Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
  
 
 0.755
atoB
acetyl-CoA acetyltransferase.
    
 0.739
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Can use NAD(+) and NADP(+) with similar specific activity. Belongs to the LDH/MDH superfamily.
  
 
 0.733
dnaK
Chaperone DnaK; Acts as a chaperone.
  
 0.705
lor/sdh
Predicted lysine-oxoglutarate reductase/saccharopine dehydrogenase.
     
 0.695
Your Current Organism:
Methanothermobacter marburgensis
NCBI taxonomy Id: 79929
Other names: M. marburgensis str. Marburg, Methanobacterium thermoautotrophicum (strain Marburg / DSM 2133), Methanobacterium thermoautotrophicum str. Marburg, Methanothermobacter marburgensis str. Marburg, Methanothermobacter marburgensis strain Marburg
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