fmdE protein (Methanothermobacter marburgensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

fmdE

Molybdenum containing formylmethanofuran dehydrogenase, subunit E. (180 aa)

Predicted Functional Partners:

fmdC

0.978

fdhA1

0.927

fmdB

0.878

fdhB

0.822

fdhA2

0.784

cdhA1

0.729

cdhA3

0.724

cdhB2

0.723

cdhA2

0.722

cdhB1

0.720

Your Current Organism:

Methanothermobacter marburgensis

NCBI taxonomy Id: 79929
Other names: M. marburgensis str. Marburg, Methanobacterium thermoautotrophicum (strain Marburg / DSM 2133), Methanobacterium thermoautotrophicum str. Marburg, Methanothermobacter marburgensis str. Marburg, Methanothermobacter marburgensis strain Marburg

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cdhA1	cdhA2	MTBMA_c02870	MTBMA_c14200	acetyl-CoA decarbonylase/synthase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	acetyl-CoA decarbonylase/synthase complex, alpha subunit.	0.904
cdhA1	cdhA3	MTBMA_c02870	MTBMA_c14210	acetyl-CoA decarbonylase/synthase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	acetyl-CoA decarbonylase/synthase complex, alpha subunit.	0.904
cdhA1	cdhB1	MTBMA_c02870	MTBMA_c02880	acetyl-CoA decarbonylase/synthase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	acetyl-CoA decarbonylase/synthase, subunit epsilon; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear; it may have a stabilizing role within the alpha(2)epsilon(2) component and/or be involved in electron transfer to FAD during a potential FAD-mediated CO oxidation. Belongs to the CdhB family.	0.999
cdhA1	cdhB2	MTBMA_c02870	MTBMA_c14190	acetyl-CoA decarbonylase/synthase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	acetyl-CoA decarbonylase/synthase complex, subunit epsilon.	0.997
cdhA1	fdhA1	MTBMA_c02870	MTBMA_c01380	acetyl-CoA decarbonylase/synthase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	Predicted formate dehydrogenase, alpha chain.	0.912
cdhA1	fdhA2	MTBMA_c02870	MTBMA_c15230	acetyl-CoA decarbonylase/synthase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	Formate dehydrogenase, alpha subunit.	0.912
cdhA1	fdhB	MTBMA_c02870	MTBMA_c15220	acetyl-CoA decarbonylase/synthase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	Formate dehydrogenase, beta subunit.	0.924
cdhA1	fmdB	MTBMA_c02870	MTBMA_c13070	acetyl-CoA decarbonylase/synthase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	Molybdenum containing formylmethanofuran dehydrogenase, subunit B.	0.789
cdhA1	fmdC	MTBMA_c02870	MTBMA_c13060	acetyl-CoA decarbonylase/synthase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	Molybdenum containing formylmethanofuran dehydrogenase, subunit C; Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR). Can only oxidize formylmethanofuran. This enzyme is oxygen-labile. In the N-terminal section; belongs to the FwdC/FmdC family.	0.765
cdhA1	fmdE	MTBMA_c02870	MTBMA_c13050	acetyl-CoA decarbonylase/synthase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	Molybdenum containing formylmethanofuran dehydrogenase, subunit E.	0.729
cdhA2	cdhA1	MTBMA_c14200	MTBMA_c02870	acetyl-CoA decarbonylase/synthase complex, alpha subunit.	acetyl-CoA decarbonylase/synthase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.	0.904
cdhA2	cdhA3	MTBMA_c14200	MTBMA_c14210	acetyl-CoA decarbonylase/synthase complex, alpha subunit.	acetyl-CoA decarbonylase/synthase complex, alpha subunit.	0.998
cdhA2	cdhB1	MTBMA_c14200	MTBMA_c02880	acetyl-CoA decarbonylase/synthase complex, alpha subunit.	acetyl-CoA decarbonylase/synthase, subunit epsilon; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear; it may have a stabilizing role within the alpha(2)epsilon(2) component and/or be involved in electron transfer to FAD during a potential FAD-mediated CO oxidation. Belongs to the CdhB family.	0.996
cdhA2	cdhB2	MTBMA_c14200	MTBMA_c14190	acetyl-CoA decarbonylase/synthase complex, alpha subunit.	acetyl-CoA decarbonylase/synthase complex, subunit epsilon.	0.998
cdhA2	fdhA1	MTBMA_c14200	MTBMA_c01380	acetyl-CoA decarbonylase/synthase complex, alpha subunit.	Predicted formate dehydrogenase, alpha chain.	0.912
cdhA2	fdhA2	MTBMA_c14200	MTBMA_c15230	acetyl-CoA decarbonylase/synthase complex, alpha subunit.	Formate dehydrogenase, alpha subunit.	0.912
cdhA2	fdhB	MTBMA_c14200	MTBMA_c15220	acetyl-CoA decarbonylase/synthase complex, alpha subunit.	Formate dehydrogenase, beta subunit.	0.913
cdhA2	fmdB	MTBMA_c14200	MTBMA_c13070	acetyl-CoA decarbonylase/synthase complex, alpha subunit.	Molybdenum containing formylmethanofuran dehydrogenase, subunit B.	0.786
cdhA2	fmdC	MTBMA_c14200	MTBMA_c13060	acetyl-CoA decarbonylase/synthase complex, alpha subunit.	Molybdenum containing formylmethanofuran dehydrogenase, subunit C; Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR). Can only oxidize formylmethanofuran. This enzyme is oxygen-labile. In the N-terminal section; belongs to the FwdC/FmdC family.	0.757
cdhA2	fmdE	MTBMA_c14200	MTBMA_c13050	acetyl-CoA decarbonylase/synthase complex, alpha subunit.	Molybdenum containing formylmethanofuran dehydrogenase, subunit E.	0.722

page 1 of 6

Server load: low (22%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2025

Credits

Access

Info

About