| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADL58944.1 | eif2A | MTBMA_c13570 | MTBMA_c16940 | Conserved hypothetical protein. | Predicted translation initiation factor 2, alpha subunit eIF2A; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. | 0.979 |
| ADL58944.1 | pan | MTBMA_c13570 | MTBMA_c11240 | Conserved hypothetical protein. | Predicted proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promot [...] | 0.999 |
| ADL58944.1 | psmA | MTBMA_c13570 | MTBMA_c10730 | Conserved hypothetical protein. | Predicted proteasome, subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.952 |
| ADL58944.1 | psmB | MTBMA_c13570 | MTBMA_c15800 | Conserved hypothetical protein. | Predicted proteasome, subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.952 |
| ADL58944.1 | rpl40e | MTBMA_c13570 | MTBMA_c09420 | Conserved hypothetical protein. | 50S ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.987 |
| ADL58944.1 | rps15p | MTBMA_c13570 | MTBMA_c00110 | Conserved hypothetical protein. | 30S ribosomal protein S15P. | 0.949 |
| ADL58944.1 | rps19p | MTBMA_c13570 | MTBMA_c04950 | Conserved hypothetical protein. | 30S ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. | 0.951 |
| ADL58944.1 | rps28e | MTBMA_c13570 | MTBMA_c07060 | Conserved hypothetical protein. | 30S ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family. | 0.949 |
| ADL58944.1 | rps3p | MTBMA_c13570 | MTBMA_c04970 | Conserved hypothetical protein. | 30S ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. | 0.951 |
| ADL58944.1 | rps8p | MTBMA_c13570 | MTBMA_c05070 | Conserved hypothetical protein. | 30S ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. | 0.947 |
| eif2A | ADL58944.1 | MTBMA_c16940 | MTBMA_c13570 | Predicted translation initiation factor 2, alpha subunit eIF2A; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. | Conserved hypothetical protein. | 0.979 |
| eif2A | rpl40e | MTBMA_c16940 | MTBMA_c09420 | Predicted translation initiation factor 2, alpha subunit eIF2A; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. | 50S ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.781 |
| eif2A | rps15p | MTBMA_c16940 | MTBMA_c00110 | Predicted translation initiation factor 2, alpha subunit eIF2A; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. | 30S ribosomal protein S15P. | 0.996 |
| eif2A | rps19p | MTBMA_c16940 | MTBMA_c04950 | Predicted translation initiation factor 2, alpha subunit eIF2A; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. | 30S ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. | 0.998 |
| eif2A | rps28e | MTBMA_c16940 | MTBMA_c07060 | Predicted translation initiation factor 2, alpha subunit eIF2A; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. | 30S ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family. | 0.997 |
| eif2A | rps3p | MTBMA_c16940 | MTBMA_c04970 | Predicted translation initiation factor 2, alpha subunit eIF2A; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. | 30S ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. | 0.999 |
| eif2A | rps8p | MTBMA_c16940 | MTBMA_c05070 | Predicted translation initiation factor 2, alpha subunit eIF2A; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. | 30S ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. | 0.998 |
| pan | ADL58944.1 | MTBMA_c11240 | MTBMA_c13570 | Predicted proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promot [...] | Conserved hypothetical protein. | 0.999 |
| pan | psmA | MTBMA_c11240 | MTBMA_c10730 | Predicted proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promot [...] | Predicted proteasome, subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.984 |
| pan | psmB | MTBMA_c11240 | MTBMA_c15800 | Predicted proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promot [...] | Predicted proteasome, subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.976 |