close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mvhBF420-non-reducing hydrogenase, subunit B, polyferredoxin. (412 aa)    
Predicted Functional Partners:
mvhG
F420-non-reducing hydrogenase, subunit G; Part of a complex that provides reducing equivalents for heterodisulfide reductase; Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
 
  
 0.999
hdrC
CoB-CoM heterodisulfide reductase, subunit C; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
  
  
 0.997
mvhA
F420-non-reducing hydrogenase, subunit A; Part of a complex that provides reducing equivalents for heterodisulfide reductase.
  
  
 0.991
hdrB
CoB-CoM heterodisulfide reductase, subunit B; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B); Belongs to the HdrB family.
   
  
 0.959
mvhD
F420-non-reducing hydrogenase, subunit D; Part of a complex that provides reducing equivalents for heterodisulfide reductase. MvhD may form the contact site to heterodisulfide reductase.
  
  
 0.888
fwdA
Tungsten formylmethanofuran dehydrogenase, subunit A.
      
 0.880
hdrA
CoB-CoM heterodisulfide reductase iron-sulfur, subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B); Belongs to the HdrA family.
  
  
 0.875
ADL59100.1
Methyl viologen-reducing hydrogenase, subunit D-related protein.
  
  
 0.628
ehaQ
Energy-converting hydrogenase A, subunit Q.
 
  
0.528
fdhB
Formate dehydrogenase, beta subunit.
 
  
 0.521
Your Current Organism:
Methanothermobacter marburgensis
NCBI taxonomy Id: 79929
Other names: M. marburgensis str. Marburg, Methanobacterium thermoautotrophicum (strain Marburg / DSM 2133), Methanobacterium thermoautotrophicum str. Marburg, Methanothermobacter marburgensis str. Marburg, Methanothermobacter marburgensis strain Marburg
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.