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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
psmBPredicted proteasome, subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (210 aa)    
Predicted Functional Partners:
psmA
Predicted proteasome, subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
 
0.981
pan
Predicted proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promot [...]
  
 0.976
ADL58944.1
Conserved hypothetical protein.
   
 0.952
rpl40e
50S ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.889
cdcH
Predicted cell division protein 48.
  
 0.859
ADL59160.1
Predicted metal-dependent RNase.
     
 0.783
ef1B
Elongation factor 1-beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
  
 
 0.656
thsA
Thermosome, subunit alpha (chaperonin subunit); Belongs to the TCP-1 chaperonin family.
 
 
 0.636
thsB
Thermosome, subunit beta (chaperonin subunit); Belongs to the TCP-1 chaperonin family.
 
 
 0.633
ADL59259.1
Conserved hypothetical protein.
 
 
 
 0.615
Your Current Organism:
Methanothermobacter marburgensis
NCBI taxonomy Id: 79929
Other names: M. marburgensis str. Marburg, Methanobacterium thermoautotrophicum (strain Marburg / DSM 2133), Methanobacterium thermoautotrophicum str. Marburg, Methanothermobacter marburgensis str. Marburg, Methanothermobacter marburgensis strain Marburg
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.