STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypFPredicted hydrogenase maturation factor HypF. (766 aa)    
Predicted Functional Partners:
hypA
Hydrogenase maturation factor HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
   
 0.999
hypB
Hydrogenase maturation factor HypB.
 
   
 0.998
frhA
F420-reducing hydrogenase, subunit alpha; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 
 0.998
hypE
Hydrogenase maturation factor HypE.
 
 
 0.996
mvhA
F420-non-reducing hydrogenase, subunit A; Part of a complex that provides reducing equivalents for heterodisulfide reductase.
 
 
 
 0.987
hypD
Predicted hydrogenase expression/formation protein HypD.
 
  
 0.978
hypC
Hydrogenase maturation factor HypC.
 
 
 0.890
ehbN
Energy-converting hydrogenase B, subunit N.
     
 0.836
hycI
Hydrogenase maturation protease.
 
   
 0.826
ehaO
Energy-converting hydrogenase A, subunit O.
     
 0.753
Your Current Organism:
Methanothermobacter marburgensis
NCBI taxonomy Id: 79929
Other names: M. marburgensis str. Marburg, Methanobacterium thermoautotrophicum (strain Marburg / DSM 2133), Methanobacterium thermoautotrophicum str. Marburg, Methanothermobacter marburgensis str. Marburg, Methanothermobacter marburgensis strain Marburg
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.