| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADL58247.1 | ADL59289.1 | MTBMA_c06520 | MTBMA_c17200 | Predicted ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. | Predicted peptidyl-prolyl cis-trans isomerase. | 0.942 |
| ADL58247.1 | dnaJ | MTBMA_c06520 | MTBMA_c16760 | Predicted ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. | Chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | 0.823 |
| ADL58247.1 | fusA | MTBMA_c06520 | MTBMA_c14440 | Predicted ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. | Protein translation elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF- [...] | 0.954 |
| ADL58247.1 | rpl11p | MTBMA_c06520 | MTBMA_c02580 | Predicted ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. | 50S ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. | 0.859 |
| ADL58247.1 | rpl13p | MTBMA_c06520 | MTBMA_c05280 | Predicted ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. | 50S ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.893 |
| ADL58247.1 | valS | MTBMA_c06520 | MTBMA_c11620 | Predicted ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. | 0.407 |
| ADL59289.1 | ADL58247.1 | MTBMA_c17200 | MTBMA_c06520 | Predicted peptidyl-prolyl cis-trans isomerase. | Predicted ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. | 0.942 |
| ADL59289.1 | dnaJ | MTBMA_c17200 | MTBMA_c16760 | Predicted peptidyl-prolyl cis-trans isomerase. | Chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | 0.955 |
| ADL59289.1 | fadD | MTBMA_c17200 | MTBMA_c10380 | Predicted peptidyl-prolyl cis-trans isomerase. | acyl-CoA synthetase. | 0.895 |
| ADL59289.1 | flpA | MTBMA_c17200 | MTBMA_c16000 | Predicted peptidyl-prolyl cis-trans isomerase. | Predicted fibrillarin-like rRNA/tRNA 2'-O-methyltransferase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. | 0.942 |
| ADL59289.1 | fusA | MTBMA_c17200 | MTBMA_c14440 | Predicted peptidyl-prolyl cis-trans isomerase. | Protein translation elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF- [...] | 0.897 |
| ADL59289.1 | ndk | MTBMA_c17200 | MTBMA_c07080 | Predicted peptidyl-prolyl cis-trans isomerase. | Predicted nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.907 |
| ADL59289.1 | rpl11p | MTBMA_c17200 | MTBMA_c02580 | Predicted peptidyl-prolyl cis-trans isomerase. | 50S ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. | 0.879 |
| ADL59289.1 | rpl13p | MTBMA_c17200 | MTBMA_c05280 | Predicted peptidyl-prolyl cis-trans isomerase. | 50S ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.888 |
| ADL59289.1 | sodA | MTBMA_c17200 | MTBMA_c06110 | Predicted peptidyl-prolyl cis-trans isomerase. | Superoxide dismutase; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family. | 0.892 |
| ADL59289.1 | valS | MTBMA_c17200 | MTBMA_c11620 | Predicted peptidyl-prolyl cis-trans isomerase. | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. | 0.974 |
| dnaJ | ADL58247.1 | MTBMA_c16760 | MTBMA_c06520 | Chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | Predicted ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. | 0.823 |
| dnaJ | ADL59289.1 | MTBMA_c16760 | MTBMA_c17200 | Chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | Predicted peptidyl-prolyl cis-trans isomerase. | 0.955 |
| dnaJ | fadD | MTBMA_c16760 | MTBMA_c10380 | Chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | acyl-CoA synthetase. | 0.899 |
| dnaJ | flpA | MTBMA_c16760 | MTBMA_c16000 | Chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | Predicted fibrillarin-like rRNA/tRNA 2'-O-methyltransferase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. | 0.823 |