Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
ADL59304.1FwdE-related protein. (171 aa)    
Predicted Functional Partners:
fdhA1
Predicted formate dehydrogenase, alpha chain.
  
 
 0.921
ADL57970.1
Conserved hypothetical protein.
      0.889
cbiM1
Predicted cobalt transport protein.
 
    0.875
fdhA2
Formate dehydrogenase, alpha subunit.
  
 
 0.725
fdhB
Formate dehydrogenase, beta subunit.
   
 
 0.691
ftr
Formylmethanofuran-tetrahydromethanopterin formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family.
     
 0.685
ehaS
Energy-converting hydrogenase A, subunit S; Belongs to the FTR family.
     
 0.675
ADL59305.1
Predicted ATP-dependent helicase.
       0.675
cdhA1
acetyl-CoA decarbonylase/synthase, subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.
     
 0.667
cdhA2
acetyl-CoA decarbonylase/synthase complex, alpha subunit.
     
 0.667
Your Current Organism:
Methanothermobacter marburgensis
NCBI taxonomy Id: 79929
Other names: M. marburgensis str. Marburg, Methanobacterium thermoautotrophicum (strain Marburg / DSM 2133), Methanobacterium thermoautotrophicum str. Marburg, Methanothermobacter marburgensis str. Marburg, Methanothermobacter marburgensis strain Marburg
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