STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADL59333.1Conserved hypothetical protein. (130 aa)    
Predicted Functional Partners:
eif5A
Translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
  
 0.912
ADL59334.1
Conserved hypothetical protein containing a ferredoxin domain.
       0.537
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro- aldol mechanism; Belongs to the SHMT family.
       0.537
rps8e
30S ribosomal protein S8e.
   
    0.482
dys
Predicted deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
  
 
 0.476
ADL58843.1
Predicted GTPase.
   
    0.472
guaAB
GMP synthase, subunit B; Catalyzes the synthesis of GMP from XMP.
  
    0.471
ADL58533.1
Tetratricopeptide repeat domain-containing protein.
 
 
 0.452
ADL57615.1
Predicted methyltransferase.
   
    0.450
ADL58534.1
Predicted sensory transduction regulatory protein.
     
 0.440
Your Current Organism:
Methanothermobacter marburgensis
NCBI taxonomy Id: 79929
Other names: M. marburgensis str. Marburg, Methanobacterium thermoautotrophicum (strain Marburg / DSM 2133), Methanobacterium thermoautotrophicum str. Marburg, Methanothermobacter marburgensis str. Marburg, Methanothermobacter marburgensis strain Marburg
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.