STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADL59349.1Predicted glycyl radical-activating enzyme. (335 aa)    
Predicted Functional Partners:
ADL58842.1
Conserved hypothetical protein.
     0.967
ADL58129.1
Conserved hypothetical protein; Belongs to the MEMO1 family.
     0.954
thiL
Predicted thiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
       0.826
ADL59352.1
Predicted nucleic acid-binding protein.
     
 0.721
cbiX
Predicted sirohydrochlorin cobaltchelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin.
  
    0.718
nrdD
Anaerobic ribonucleotide-triphosphate reductase.
  
  
 0.697
ADL58955.1
Predicted alcohol dehydrogenase.
  
  
 0.600
ADL58714.1
Predicted DNA modification methylase.
     
 0.442
ADL57826.1
Conserved hypothetical protein.
  
    0.422
ADL58950.1
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
  
 0.419
Your Current Organism:
Methanothermobacter marburgensis
NCBI taxonomy Id: 79929
Other names: M. marburgensis str. Marburg, Methanobacterium thermoautotrophicum (strain Marburg / DSM 2133), Methanobacterium thermoautotrophicum str. Marburg, Methanothermobacter marburgensis str. Marburg, Methanothermobacter marburgensis strain Marburg
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.