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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5K095_ASTMXEndoplasmic reticulum to nucleus signaling 1. (1041 aa)    
Predicted Functional Partners:
Xbp1
X-box binding protein 1.
    
 0.948
traf2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.940
LOC103036375
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.940
LOC103038360
Si:ch211-1i11.3.
   
0.932
map3k5
Mitogen-activated protein kinase kinase kinase 5.
   
0.932
hspa5
Heat shock protein 5; Belongs to the heat shock protein 70 family.
    
 0.907
ENSAMXP00000028082
CARD domain-containing protein.
     
  0.900
ENSAMXP00000045985
Uncharacterized protein.
     
 
0.900
LOC103025011
ATP-binding cassette, sub-family E (OABP), member 1.
   
 0.617
ABCE1
ATP binding cassette subfamily E member 1.
   
 0.617
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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