Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
W5K095_ASTMXEndoplasmic reticulum to nucleus signaling 1. (1041 aa)    
Predicted Functional Partners:
traf2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.977
LOC103036375
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.977
Xbp1
X-box binding protein 1.
    
 0.972
map3k5
Mitogen-activated protein kinase kinase kinase 5.
    
 0.967
W5LGF4_ASTMX
Endoplasmic reticulum to nucleus signaling 2.
  
  
 
0.964
LOC103038360
Si:ch211-1i11.3.
    
 0.945
hspa5
Heat shock protein 5; Belongs to the heat shock protein 70 family.
    
 0.929
sec63
SEC63 homolog, protein translocation regulator.
    
 
 0.734
LOC103045252
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.723
syvn1
Synovial apoptosis inhibitor 1, synoviolin.
    
 
 0.636
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.