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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5K0G8_ASTMXRaf-1 proto-oncogene, serine/threonine kinase a. (642 aa)    
Predicted Functional Partners:
map2k1
Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
   
0.798
map2k5
Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily.
   
0.797
map2k2
Mitogen-activated protein kinase kinase 2b; Belongs to the protein kinase superfamily.
   
0.797
LOC103022868
RAP1A, member of RAS oncogene family b.
   
 0.766
rap1b
RAP1B, member of RAS oncogene family.
   
 0.766
rap1a
RAP1A, member of RAS oncogene family a.
   
 0.766
ppp5c
Serine/threonine-protein phosphatase.
   
 0.759
nras
NRAS proto-oncogene, GTPase.
   
 0.755
ywhab
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a; Belongs to the 14-3-3 family.
   
 0.752
LOC107197738
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b; Belongs to the 14-3-3 family.
   
 0.752
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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