close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nkx6-1NK6 homeobox 1. (326 aa)    
Predicted Functional Partners:
ENSAMXP00000042842
Neurogenin 3.
   
  
 0.581
ENSAMXP00000037985
Oligodendrocyte lineage transcription factor 2.
   
  
 0.568
ptf1a
Pancreas associated transcription factor 1a.
      
 0.563
W5L6B6_ASTMX
Neurogenic differentiation factor.
   
  
 0.528
Gcg
Glucagon b.
      
 0.520
pdx1
Pancreatic and duodenal homeobox 1.
  
0.485
LOC107197780
NK2 homeobox 2b.
   
  
0.473
shh
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
  
 0.449
onecut1
One cut domain family member.
   
 
 0.405
irx3
Iroquois homeobox 3b.
      
 0.404
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.