close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnaseh2cRibonuclease H2, subunit C. (135 aa)    
Predicted Functional Partners:
rnaseh2b
Ribonuclease H2, subunit B.
   
 0.979
W5JYN8_ASTMX
Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
   
 
 0.967
ctdp1
RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.
    
 
 0.578
skiv2l
SKI2 homolog, superkiller viralicidic activity 2-like.
      
 0.574
atrip
ATR interacting protein.
      
 0.552
ENSAMXP00000052495
Damage-specific DNA binding protein 1.
      
 0.511
LOC103038624
Zgc:77849.
      
 0.441
c2h16orf72
Zgc:66160.
      
 0.441
POLR2E
RNA polymerase II subunit E.
   
  
 0.438
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: low (28%) [HD]