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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppm1fProtein phosphatase, Mg2+/Mn2+ dependent, 1F. (419 aa)    
Predicted Functional Partners:
crnkl1
Crooked neck pre-mRNA splicing factor 1.
   
  
 0.579
ess2
Ess-2 splicing factor homolog.
   
  
 0.579
ENSAMXP00000049721
Activating signal cointegrator 1 complex subunit 2.
      
 0.576
kansl2
KAT8 regulatory NSL complex subunit 2.
   
  
 0.575
ccdc92
Coiled-coil domain containing 92.
      
 0.574
Dgcr2
DiGeorge syndrome critical region gene 2.
      
 0.573
prcc
Proline rich mitotic checkpoint control factor.
      
 0.572
fem1c
Fem-1 homolog c (C. elegans).
   
 
 0.550
FEM1A
Fem-1 homolog A.
   
 
 0.550
fem1b
Fem-1 homolog b (C. elegans).
   
 
 0.550
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.