Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
W5K144_ASTMXNeuronal differentiation 6a. (348 aa)    
Predicted Functional Partners:
atf3
Activating transcription factor 3.
      
 0.500
W5LTZ4_ASTMX
Insulinoma-associated 1b.
   
 0.497
ENSAMXP00000027435
Insulinoma-associated 1a.
   
 0.497
LOC103028433
BHLH domain-containing protein.
    
 
 0.484
tcf3
Transcription factor 3a.
    
 
 0.484
ENSAMXP00000046200
BHLH domain-containing protein.
    
 
 0.484
ENSAMXP00000049713
Transcription factor 12.
    
 
 0.484
TCF4
Transcription factor 4.
    
 
 0.484
nes
IF rod domain-containing protein; Belongs to the intermediate filament family.
      
 0.470
LOC107197780
NK2 homeobox 2b.
   
 0.466
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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