close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ca10Carbonic anhydrase Xb; Belongs to the alpha-carbonic anhydrase family. (311 aa)    
Predicted Functional Partners:
rpf2
Ribosome production factor 2 homolog.
   
 
 0.626
utp18
WD_REPEATS_REGION domain-containing protein.
   
  
 0.592
W5K1E6_ASTMX
Cell division cycle and apoptosis regulator 1.
      
 0.574
Rrs1
Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.
   
 
 0.529
grwd1
Glutamate-rich WD repeat containing 1.
   
  
 0.525
Mgp
Gla domain-containing protein.
      
 0.495
rpl11
Ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family.
    
 
 0.482
nle1
Notchless homolog 1 (Drosophila).
   
  
 0.459
rpl5
Ribosomal protein L5b.
    
 
 0.450
gtpbp4
Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
   
  
 0.450
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.