close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103041322Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (393 aa)    
Predicted Functional Partners:
axin1
Axin 1.
    
 0.949
LOC103042974
Axin 2 (conductin, axil).
    
 0.949
axin2
Uncharacterized protein.
    
 0.949
W5K6T9_ASTMX
LTV1 ribosome biogenesis factor.
    
 0.932
smo
Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.
    
  0.907
LOC103022611
Forkhead box O4.
    
  0.902
foxo3
Forkhead box O3b.
    
  0.902
LOC103026113
Forkhead box O3A.
    
  0.902
LOC103046520
Forkhead box O1 b.
    
  0.902
foxo1
Forkhead box O1 a.
    
  0.902
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: low (40%) [HD]