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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5K1C8_ASTMXGTPase activating protein and VPS9 domains 1. (1407 aa)    
Predicted Functional Partners:
rabep1
Rabaptin, RAB GTPase binding effector protein 1.
   
 0.889
rabep2
Rabaptin, RAB GTPase binding effector protein 2.
   
 0.809
rab21
RAB21, member RAS oncogene family.
   
 0.794
LOC103034209
RAB5B, member RAS oncogene family.
    
 0.789
LOC103038585
RAB5A, member RAS oncogene family, b.
    
 0.789
LOC103035226
Uncharacterized protein.
    
 0.789
rab5c
RAB5C, member RAS oncogene family.
    
 0.789
LOC103027170
RAB5A, member RAS oncogene family, a.
    
 0.789
vps29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
    
 
 0.704
W5K2B1_ASTMX
Alsin Rho guanine nucleotide exchange factor ALS2 a.
    
 0.699
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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