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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ascc3Activating signal cointegrator 1 complex subunit 3. (2149 aa)    
Predicted Functional Partners:
ENSAMXP00000049721
Activating signal cointegrator 1 complex subunit 2.
    
 0.982
prpf8
Pre-mRNA processing factor 8.
   
 0.980
prpf6
PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae).
   
 0.966
trip4
Thyroid hormone receptor interactor 4.
    
 
 0.955
ascc1
Activating signal cointegrator 1 complex subunit 1.
    
 0.947
Snrpf
Small nuclear ribonucleoprotein polypeptide F.
   
 0.931
snrpd3
Small nuclear ribonucleoprotein Sm D3.
   
 0.927
snrpd2
Small nuclear ribonucleoprotein Sm D2.
   
 0.924
snrpg
Small nuclear ribonucleoprotein G.
   
  0.912
snrnp40
Small nuclear ribonucleoprotein 40 (U5).
   
 0.908
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.