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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103039742Period circadian clock 2. (1439 aa)    
Predicted Functional Partners:
LOC103044559
Cryptochrome circadian regulator 2.
   
 0.820
timeless
Timeless circadian clock.
   
 0.817
LOC103034890
Cryptochrome circadian regulator 5.
   
 0.798
W5KD92_ASTMX
Cryptochrome circadian regulator 1a.
   
 0.778
W5K4A8_ASTMX
Cryptochrome DASH.
   
 0.776
W5KNK0_ASTMX
Photolyase/cryptochrome alpha/beta domain-containing protein.
   
 0.775
Cry1
Cryptochrome circadian regulator 1b.
   
 0.751
LOC103041322
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 0.746
LOC103024972
Casein kinase 1, epsilon; Belongs to the protein kinase superfamily.
    
 0.746
LOC103030301
Casein kinase 1, delta b; Belongs to the protein kinase superfamily.
    
 0.746
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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