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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103033740Tyrosine-protein kinase. (450 aa)    
Predicted Functional Partners:
ENSAMXP00000054113
Phosphoprotein membrane anchor with glycosphingolipid microdomains 1.
    
 0.916
ptpn12
Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades.
   
 0.854
LOC103047683
Leupaxin.
   
 0.710
lck
Tyrosine-protein kinase.
  
0.690
TGFB1I1
Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.
   
 0.684
ENSAMXP00000053993
Paxillin b.
   
 0.684
ENSAMXP00000051608
Tyrosine-protein kinase.
  
0.681
SRC
Tyrosine-protein kinase.
  
0.679
LOC103038924
Tyrosine-protein kinase.
  
0.679
W5LAG0_ASTMX
SHC (Src homology 2 domain containing) transforming protein 1.
   
0.676
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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