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Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DspDesmoplakin a. (2521 aa)    
Predicted Functional Partners:
itgb4
Integrin beta.
   
 0.727
LOC103045821
Junction plakoglobin a.
   
 0.713
LOC103034091
Desmocollin 2 like; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
   
 0.676
W5K1Q3_ASTMX
Integrin beta; Belongs to the integrin beta chain family.
   
 0.634
W5KDJ8_ASTMX
Junction plakoglobin b.
   
 0.626
pkp2
Plakophilin 2.
   
 0.602
sptan1
Spectrin alpha, non-erythrocytic 1.
   
 0.542
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 0.535
Pkp1
Plakophilin 1b.
   
 0.531
atp2b2
Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
   
  
 0.523
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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