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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103027671ArfGAP with SH3 domain, ankyrin repeat and PH domain 3. (973 aa)    
Predicted Functional Partners:
appl1
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.
   
 
0.673
exoc7
Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
     
 0.634
ARF6
ADP ribosylation factor 6.
    
 0.528
W5LTZ3_ASTMX
ADP-ribosylation factor 6b; Belongs to the small GTPase superfamily. Arf family.
    
 0.528
exoc1
Exocyst complex component 1.
   
 
  0.512
W5KFC3_ASTMX
RAB11 family interacting protein 4 (class II) b.
    
 0.501
LOC103025004
RAB11 family interacting protein 4 (class II) a.
    
 0.501
rab11fip3
RAB11 family interacting protein 3 (class II).
    
 0.501
ENSAMXP00000027980
Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.
     
 0.501
rab11a
RAB11a, member RAS oncogene family.
    
 0.473
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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