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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5K2B1_ASTMXAlsin Rho guanine nucleotide exchange factor ALS2 a. (1581 aa)    
Predicted Functional Partners:
LOC103021796
Uncharacterized protein.
    
 0.955
LOC103027984
RAB guanine nucleotide exchange factor (GEF) 1, like.
    
 0.955
rabgef1
RAB guanine nucleotide exchange factor (GEF) 1.
    
 0.955
ENSAMXP00000033034
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 0.799
W5K1C8_ASTMX
GTPase activating protein and VPS9 domains 1.
    
 0.699
zfand4
Zinc finger, AN1-type domain 4.
    
 0.687
W5K6B4_ASTMX
Exportin 1 (CRM1 homolog, yeast) a.
    
 
 0.622
XPO5
Exportin 5.
    
 
 0.622
LOC103021592
Exportin 1 (CRM1 homolog, yeast) b.
    
 
 0.622
W5L2P3_ASTMX
Radial spoke head component 4A.
    
 
 0.622
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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