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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5K2D7_ASTMX5-hydroxytryptamine (serotonin) receptor 7c. (386 aa)    
Predicted Functional Partners:
LOC103040890
Uncharacterized protein.
    
 0.864
ENSAMXP00000035728
Uncharacterized protein.
    
 0.627
GNG4
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
  0.455
LOC103030920
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
  0.455
Rhobtb3
Si:dkey-6b12.5.
    
  0.451
ENSAMXP00000050689
BTB domain-containing protein.
    
  0.451
LOC103030165
WD_REPEATS_REGION domain-containing protein.
    
  0.415
gnb1
Guanine nucleotide binding protein (G protein), beta polypeptide 1a.
    
  0.415
LOC103029911
Guanine nucleotide binding protein (G protein), beta polypeptide 4b.
    
  0.415
LOC103031762
Guanine nucleotide binding protein (G protein), beta polypeptide 2.
    
  0.415
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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