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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5K2E5_ASTMXTranscription factor SOX. (393 aa)    
Predicted Functional Partners:
W5L9B2_ASTMX
Transcription factor 7.
    
0.524
lef1
Lymphoid enhancer-binding factor 1.
    
0.513
ENSAMXP00000040707
POU domain, class 5, transcription factor 3.
    
 0.496
LOC103034575
Catenin, beta 2.
    
 0.475
Sox6
SRY-box transcription factor 6.
    
0.475
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 0.475
LOC103022374
Transcription factor 7 like 1b.
    
0.469
tcf7l2
Transcription factor 7 like 2.
    
0.469
W5KDJ8_ASTMX
Junction plakoglobin b.
    
 0.449
LOC103045821
Junction plakoglobin a.
    
 0.449
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.