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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fbxl5F-box and leucine-rich repeat protein 5. (681 aa)    
Predicted Functional Partners:
skp1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.987
ireb2
Iron-responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family.
    
 0.956
aco1
Aconitase 1, soluble.
    
 0.943
LOC103029821
Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.
    
 0.833
ACO2
Aconitase 2.
    
 0.833
W5KX87_ASTMX
Cullin 3a; Belongs to the cullin family.
    
 0.831
cul3
Cullin 3b; Belongs to the cullin family.
    
 0.831
LOC111194478
Cullin 1a; Belongs to the cullin family.
    
 0.831
cul1
Cullin 1b; Belongs to the cullin family.
    
 0.831
Rbx1
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.749
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.