close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tmem231Transmembrane protein 231. (309 aa)    
Predicted Functional Partners:
b9d2
B9 domain containing 2.
   
 
 0.878
b9d1
B9 protein domain 1.
   
 
 0.861
W5JZZ7_ASTMX
Coiled-coil and C2 domain containing 2A.
    
 
 0.752
Tctn1
Tectonic family member 1.
   
 
 0.745
tmem67
Transmembrane protein 67.
   
  
 0.720
nphp1
Nephronophthisis 1.
   
  
 0.702
TMEM216
Transmembrane protein 216.
   
  
 0.699
rpgrip1l
RPGRIP1 like.
      
 0.692
tctn3
DUF1619 domain-containing protein.
   
 
 0.630
W5KIU0_ASTMX
MKS transition zone complex subunit 1.
    
 
 0.596
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.