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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sh3d21SH3 domain containing 21. (476 aa)    
Predicted Functional Partners:
rps27a
Ribosomal protein S27a.
    
  0.817
UBB
Ubiquitin B.
    
  0.814
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
  0.794
cbl
Cbl proto-oncogene, E3 ubiquitin protein ligase.
    
 0.793
cblb
Cbl proto-oncogene B, E3 ubiquitin protein ligase.
    
 0.793
LOC103042889
Cbl proto-oncogene C, E3 ubiquitin protein ligase.
    
 0.793
capzb
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
    
 
 0.774
ENSAMXP00000037764
NPHS1 adhesion molecule, nephrin.
    
 0.740
ENSAMXP00000043505
Ubiquitin-like domain-containing protein.
    
  0.737
LOC103044741
B cell linker.
    
 0.730
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.