W5K339_ASTMX protein (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

W5K339_ASTMX

SR-related CTD-associated factor 4b. (770 aa)

Predicted Functional Partners:

SETX

0.858

exosc10

0.826

Ncbp2

0.774

NCBP1

0.757

drosha

0.749

pcf11

0.720

mtrex

0.713

Zcchc7

0.708

ENSAMXP00000035178

0.703

polr2a

0.703

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAMXP00000035178	NCBP1	ENSAMXP00000035178	ENSAMXP00000016845	Uncharacterized protein.	Nuclear cap binding protein subunit 1.	0.693
ENSAMXP00000035178	Ncbp2	ENSAMXP00000035178	ENSAMXP00000039041	Uncharacterized protein.	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]	0.700
ENSAMXP00000035178	SETX	ENSAMXP00000035178	ENSAMXP00000014851	Uncharacterized protein.	Senataxin.	0.846
ENSAMXP00000035178	W5K339_ASTMX	ENSAMXP00000035178	ENSAMXP00000002000	Uncharacterized protein.	SR-related CTD-associated factor 4b.	0.703
ENSAMXP00000035178	exosc10	ENSAMXP00000035178	ENSAMXP00000014930	Uncharacterized protein.	Exosome component 10.	0.673
ENSAMXP00000035178	pcf11	ENSAMXP00000035178	ENSAMXP00000005175	Uncharacterized protein.	PCF11 cleavage and polyadenylation factor subunit.	0.928
NCBP1	ENSAMXP00000035178	ENSAMXP00000016845	ENSAMXP00000035178	Nuclear cap binding protein subunit 1.	Uncharacterized protein.	0.693
NCBP1	Ncbp2	ENSAMXP00000016845	ENSAMXP00000039041	Nuclear cap binding protein subunit 1.	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]	0.999
NCBP1	SETX	ENSAMXP00000016845	ENSAMXP00000014851	Nuclear cap binding protein subunit 1.	Senataxin.	0.783
NCBP1	W5K339_ASTMX	ENSAMXP00000016845	ENSAMXP00000002000	Nuclear cap binding protein subunit 1.	SR-related CTD-associated factor 4b.	0.757
NCBP1	Zcchc7	ENSAMXP00000016845	ENSAMXP00000012992	Nuclear cap binding protein subunit 1.	Uncharacterized protein.	0.861
NCBP1	exosc10	ENSAMXP00000016845	ENSAMXP00000014930	Nuclear cap binding protein subunit 1.	Exosome component 10.	0.816
NCBP1	mtrex	ENSAMXP00000016845	ENSAMXP00000019328	Nuclear cap binding protein subunit 1.	Mtr4 exosome RNA helicase.	0.983
NCBP1	pcf11	ENSAMXP00000016845	ENSAMXP00000005175	Nuclear cap binding protein subunit 1.	PCF11 cleavage and polyadenylation factor subunit.	0.937
NCBP1	polr2a	ENSAMXP00000016845	ENSAMXP00000039052	Nuclear cap binding protein subunit 1.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.693
Ncbp2	ENSAMXP00000035178	ENSAMXP00000039041	ENSAMXP00000035178	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]	Uncharacterized protein.	0.700
Ncbp2	NCBP1	ENSAMXP00000039041	ENSAMXP00000016845	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]	Nuclear cap binding protein subunit 1.	0.999
Ncbp2	SETX	ENSAMXP00000039041	ENSAMXP00000014851	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]	Senataxin.	0.890
Ncbp2	W5K339_ASTMX	ENSAMXP00000039041	ENSAMXP00000002000	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]	SR-related CTD-associated factor 4b.	0.774
Ncbp2	Zcchc7	ENSAMXP00000039041	ENSAMXP00000012992	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]	Uncharacterized protein.	0.557