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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Prex2Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2. (1561 aa)    
Predicted Functional Partners:
W5LKS2_ASTMX
Uncharacterized protein.
    
 0.752
LOC103034468
Cell division cycle 42.
    
 0.752
ENSAMXP00000030238
Cell division cycle 42, like.
    
 0.692
LOC103039613
Uncharacterized protein.
    
 0.692
pten
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
     
 0.583
ENSAMXP00000030758
Transmembrane phosphatase with tensin homology.
     
 0.583
LOC103046962
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
     
 0.583
rhoq
Ras homolog family member Q.
    
 0.536
Rhoh
Ras homolog family member H.
    
 0.536
rhoj
Ras homolog family member J.
    
 0.536
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.