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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5K3H8_ASTMXNeuroblastoma amplified sequence. (2244 aa)    
Predicted Functional Partners:
zw10
Zw10 kinetochore protein.
    
 0.999
rint1
RAD50 interactor 1.
    
 0.996
Stx18
Syntaxin 18.
    
 0.985
use1
Unconventional SNARE in the ER 1 homolog (S. cerevisiae).
    
 0.979
rps6kc1
Ribosomal protein S6 kinase polypeptide 1.
   
 0.894
W5KV23_ASTMX
Sorting nexin 15.
   
 0.887
LOC103023153
SEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family.
    
 0.850
ENSAMXP00000040927
BCL2 interacting protein 1b.
   
 0.848
napg
N-ethylmaleimide-sensitive factor attachment protein, gamma b.
    
 0.839
LOC103044377
N-ethylmaleimide-sensitive factor attachment protein, gamma a.
    
 0.839
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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