| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LOC103035446 | LOC103039388 | ENSAMXP00000017440 | ENSAMXP00000006099 | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b; Belongs to the enoyl-CoA hydratase/isomerase family. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.522 |
| LOC103035446 | LOC103042817 | ENSAMXP00000017440 | ENSAMXP00000048006 | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b; Belongs to the enoyl-CoA hydratase/isomerase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.546 |
| LOC103035446 | LOC103046024 | ENSAMXP00000017440 | ENSAMXP00000001857 | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b; Belongs to the enoyl-CoA hydratase/isomerase family. | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha a; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.903 |
| LOC103035446 | acadsb | ENSAMXP00000017440 | ENSAMXP00000054201 | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b; Belongs to the enoyl-CoA hydratase/isomerase family. | Acyl-CoA dehydrogenase short/branched chain. | 0.961 |
| LOC103035446 | acat2 | ENSAMXP00000017440 | ENSAMXP00000002193 | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b; Belongs to the enoyl-CoA hydratase/isomerase family. | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 0.966 |
| LOC103035446 | acox1 | ENSAMXP00000017440 | ENSAMXP00000016150 | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b; Belongs to the enoyl-CoA hydratase/isomerase family. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.970 |
| LOC103035446 | cs | ENSAMXP00000017440 | ENSAMXP00000017056 | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b; Belongs to the enoyl-CoA hydratase/isomerase family. | Citrate synthase; Belongs to the citrate synthase family. | 0.449 |
| LOC103035446 | eci2 | ENSAMXP00000017440 | ENSAMXP00000019649 | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b; Belongs to the enoyl-CoA hydratase/isomerase family. | Enoyl-CoA delta isomerase 2. | 0.596 |
| LOC103035446 | ehhadh | ENSAMXP00000017440 | ENSAMXP00000003631 | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b; Belongs to the enoyl-CoA hydratase/isomerase family. | Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.926 |
| LOC103035446 | hadh | ENSAMXP00000017440 | ENSAMXP00000010528 | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b; Belongs to the enoyl-CoA hydratase/isomerase family. | Hydroxyacyl-CoA dehydrogenase. | 0.954 |
| LOC103039388 | LOC103035446 | ENSAMXP00000006099 | ENSAMXP00000017440 | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.522 |
| LOC103039388 | LOC103042817 | ENSAMXP00000006099 | ENSAMXP00000048006 | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.950 |
| LOC103039388 | LOC103046024 | ENSAMXP00000006099 | ENSAMXP00000001857 | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha a; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.522 |
| LOC103039388 | acadsb | ENSAMXP00000006099 | ENSAMXP00000054201 | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | Acyl-CoA dehydrogenase short/branched chain. | 0.482 |
| LOC103039388 | acat2 | ENSAMXP00000006099 | ENSAMXP00000002193 | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 0.958 |
| LOC103039388 | acox1 | ENSAMXP00000006099 | ENSAMXP00000016150 | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.482 |
| LOC103039388 | cs | ENSAMXP00000006099 | ENSAMXP00000017056 | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | Citrate synthase; Belongs to the citrate synthase family. | 0.578 |
| LOC103039388 | eci2 | ENSAMXP00000006099 | ENSAMXP00000019649 | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | Enoyl-CoA delta isomerase 2. | 0.515 |
| LOC103039388 | ehhadh | ENSAMXP00000006099 | ENSAMXP00000003631 | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.949 |
| LOC103039388 | hadh | ENSAMXP00000006099 | ENSAMXP00000010528 | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | Hydroxyacyl-CoA dehydrogenase. | 0.949 |