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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ly75Lymphocyte antigen 75. (1624 aa)    
Predicted Functional Partners:
ENSAMXP00000040596
CD302 molecule.
    
 
0.596
ENSAMXP00000040707
POU domain, class 5, transcription factor 3.
      
 0.563
LOC103022011
GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. Belongs to the GDNFR family.
      
 0.519
W5KYE2_ASTMX
Integrin beta; Belongs to the integrin beta chain family.
   
 
 0.494
ENSAMXP00000047619
CD40 molecule, TNF receptor superfamily member 5.
      
 0.476
ENSAMXP00000042051
Integrin beta; Belongs to the integrin beta chain family.
   
 
 0.464
ENSAMXP00000043951
Integrin beta.
 
 
 
 0.464
gfra1
Uncharacterized protein.
      
 0.447
itga6
Integrin, alpha 6a; Belongs to the integrin alpha chain family.
     
 0.436
tnfaip3
Tumor necrosis factor, alpha-induced protein 3.
      
 0.424
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.