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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccdc174Coiled-coil domain containing 174. (469 aa)    
Predicted Functional Partners:
ENSAMXP00000035940
NRDE-2, necessary for RNA interference, domain containing.
    
 
 0.758
dld
Dihydrolipoyl dehydrogenase.
   
    0.740
ZNF830
Zinc finger protein 830.
   
    0.655
hspa5
Heat shock protein 5; Belongs to the heat shock protein 70 family.
   
  
 0.652
eif4a3
Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.
    
 
 0.637
alpk3
Uncharacterized protein.
   
  
 0.589
tatdn2
TatD DNase domain containing 2.
 
 
  
 0.584
prkrip1
PRKR interacting protein 1.
   
    0.568
nom1
Nucleolar protein with MIF4G domain 1.
      
 0.548
Dock4
Dedicator of cytokinesis 4; Belongs to the DOCK family.
     
 0.531
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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