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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fndc1Fibronectin type III domain containing 1. (1646 aa)    
Predicted Functional Partners:
appl1
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.
    
  0.937
W5KCJ1_ASTMX
Vav 3 guanine nucleotide exchange factor b.
    
 0.620
Ntng1
Netrin g1a.
    
 0.620
Ntng2
Netrin g2a.
    
 0.614
ENSAMXP00000033268
Netrin G2.
    
 0.614
LOC103046647
Netrin 5.
    
 0.614
LOC111191060
Netrin 1b.
    
 0.614
NTN1
Netrin 1.
    
 0.614
Ptk2
Protein tyrosine kinase 2aa; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.526
ENSAMXP00000042789
Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.526
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.