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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pou2f1POU domain protein. (761 aa)    
Predicted Functional Partners:
LOC103030895
POU domain protein.
     
 
0.908
Pou2f3
POU domain protein.
     
 
0.900
pou2af1
Uncharacterized protein.
    
 
 0.615
sp1
Uncharacterized protein.
    
 0.600
snapc4
Small nuclear RNA activating complex, polypeptide 4.
    
  0.579
gtf2b
General transcription factor IIB.
    
 0.526
snapc3
Small nuclear RNA activating complex, polypeptide 3.
   
 
  0.518
LOC103044365
E1A binding protein p300 a.
   
 0.501
ep300
E1A binding protein p300 b.
   
 0.501
polr3k
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
     
 0.500
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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