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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tmem129Transmembrane protein 129, E3 ubiquitin protein ligase. (358 aa)    
Predicted Functional Partners:
derl1
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
    
 0.778
ube2j2
Ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast).
    
 0.720
pex6
Peroxisomal biogenesis factor 6.
   
  0.625
derl2
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
    
 0.621
c1qtnf12
C1q and TNF related 12.
    
 0.609
Vcp
Zgc:136908; Belongs to the AAA ATPase family.
   
 0.572
Sel1l
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.
    
 
 0.536
ENSAMXP00000045039
Selenoprotein S.
    
  0.533
slbp
Stem-loop binding protein.
 
    
 0.493
enkd1
Enkurin domain containing 1.
   
  
 0.460
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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