LOC103029083 protein (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LOC103029083

Malic enzyme. (615 aa)

Predicted Functional Partners:

cs

0.970

mdh2

0.968

ENSAMXP00000042939

0.966

ENSAMXP00000046836

0.966

Pdhb

0.964

LOC103044212

0.961

ENSAMXP00000045461

0.960

LOC103033607

0.950

LOC103036835

0.950

ldhb

0.947

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAMXP00000042939	ENSAMXP00000045461	ENSAMXP00000042939	ENSAMXP00000045461	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Malate synthase-like.	0.767
ENSAMXP00000042939	ENSAMXP00000046836	ENSAMXP00000042939	ENSAMXP00000046836	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Lipoyl-binding domain-containing protein.	0.900
ENSAMXP00000042939	LOC103029083	ENSAMXP00000042939	ENSAMXP00000002456	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Malic enzyme.	0.966
ENSAMXP00000042939	LOC103033607	ENSAMXP00000042939	ENSAMXP00000028565	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Malate dehydrogenase.	0.950
ENSAMXP00000042939	LOC103036835	ENSAMXP00000042939	ENSAMXP00000053931	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Malate dehydrogenase.	0.950
ENSAMXP00000042939	LOC103044212	ENSAMXP00000042939	ENSAMXP00000042760	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.934
ENSAMXP00000042939	Pdhb	ENSAMXP00000042939	ENSAMXP00000005072	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.943
ENSAMXP00000042939	cs	ENSAMXP00000042939	ENSAMXP00000017056	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Citrate synthase; Belongs to the citrate synthase family.	0.964
ENSAMXP00000042939	ldhb	ENSAMXP00000042939	ENSAMXP00000007846	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	0.952
ENSAMXP00000042939	mdh2	ENSAMXP00000042939	ENSAMXP00000044573	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Malate dehydrogenase.	0.967
ENSAMXP00000045461	ENSAMXP00000042939	ENSAMXP00000045461	ENSAMXP00000042939	Malate synthase-like.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.767
ENSAMXP00000045461	ENSAMXP00000046836	ENSAMXP00000045461	ENSAMXP00000046836	Malate synthase-like.	Lipoyl-binding domain-containing protein.	0.767
ENSAMXP00000045461	LOC103029083	ENSAMXP00000045461	ENSAMXP00000002456	Malate synthase-like.	Malic enzyme.	0.960
ENSAMXP00000045461	LOC103033607	ENSAMXP00000045461	ENSAMXP00000028565	Malate synthase-like.	Malate dehydrogenase.	0.959
ENSAMXP00000045461	LOC103036835	ENSAMXP00000045461	ENSAMXP00000053931	Malate synthase-like.	Malate dehydrogenase.	0.959
ENSAMXP00000045461	LOC103044212	ENSAMXP00000045461	ENSAMXP00000042760	Malate synthase-like.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.810
ENSAMXP00000045461	Pdhb	ENSAMXP00000045461	ENSAMXP00000005072	Malate synthase-like.	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.656
ENSAMXP00000045461	cs	ENSAMXP00000045461	ENSAMXP00000017056	Malate synthase-like.	Citrate synthase; Belongs to the citrate synthase family.	0.992
ENSAMXP00000045461	ldhb	ENSAMXP00000045461	ENSAMXP00000007846	Malate synthase-like.	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	0.959
ENSAMXP00000045461	mdh2	ENSAMXP00000045461	ENSAMXP00000044573	Malate synthase-like.	Malate dehydrogenase.	0.968