close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tmc5Transmembrane channel-like protein. (492 aa)    
Predicted Functional Partners:
W5L6V7_ASTMX
EF-hand domain family, member B.
    
 
 0.617
ENSAMXP00000038912
Uncharacterized protein.
   
  0.445
ENSAMXP00000054481
Si:ch211-79k12.1.
   
  0.445
LOC103045102
Si:dkey-35m8.1.
     
 0.431
ENSAMXP00000031002
Dual specificity phosphatase 27; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
    
 
 0.431
vps50
VPS50 EARP/GARPII complex subunit.
      
 0.429
gpr137c
G protein-coupled receptor 137c.
      
 0.416
tmem221
Si:ch211-125m10.6.
      
 0.414
arid4a
AT rich interactive domain 4A (RBP1-like).
    
 0.401
W5K820_ASTMX
Translocase of outer mitochondrial membrane 20.
    
 0.401
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: medium (44%) [HD]