Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rnf19bRBR-type E3 ubiquitin transferase. (706 aa)    
Predicted Functional Partners:
TRAPPC2B
Trafficking protein particle complex 2B.
    
 
 0.860
UBB
Ubiquitin B.
    
 0.721
LOC103024125
Ubiquitin-conjugating enzyme E2L 3a; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.673
rnf216
Ring finger protein 216.
    
 0.667
LOC111197620
Uncharacterized protein.
    
 0.640
uckl1
Uridine-cytidine kinase; Belongs to the uridine kinase family.
    
 0.640
ENSAMXP00000037300
Uridine-cytidine kinase; Belongs to the uridine kinase family.
    
 0.640
LOC103034925
Uridine-cytidine kinase; Belongs to the uridine kinase family.
    
 0.640
cgrrf1
Cell growth regulator with ring finger domain 1.
    
 0.625
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
  0.623
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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