Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
W5K5T5_ASTMXReceptor protein-tyrosine kinase. (1232 aa)    
Predicted Functional Partners:
LOC111191028
Growth factor receptor-bound protein 2b.
    
 0.903
nrg1
Neuregulin 1.
    
 0.898
W5LAG0_ASTMX
SHC (Src homology 2 domain containing) transforming protein 1.
    
 0.897
SHC3
SHC adaptor protein 3.
    
 0.897
W5LM11_ASTMX
Neuregulin 2a.
    
 0.896
LOC111191478
Betacellulin, epidermal growth factor family member.
    
 0.894
nrg4
EGF-like domain-containing protein.
    
 0.889
LOC103042778
Neuregulin 2b.
    
 0.888
W5LEV7_ASTMX
SHC (Src homology 2 domain containing) transforming protein 2.
    
 0.875
LOC103025626
Heparin-binding EGF-like growth factor b.
    
 0.870
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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