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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spg21SPG21 abhydrolase domain containing, maspardin. (311 aa)    
Predicted Functional Partners:
spg11
SPG11 vesicle trafficking associated, spatacsin.
      
 0.693
Tecpr2
Tectonin beta-propeller repeat containing 2.
      
 0.693
LOC103032568
Tumor necrosis factor a (TNF superfamily, member 2).
      
 0.580
spg7
SPG7 matrix AAA peptidase subunit, paraplegin.
      
 0.578
Ap5z1
Adaptor related protein complex 5 subunit zeta 1.
      
 0.567
LOC103039147
Spartin b.
      
 0.541
Spart
Spartin a.
      
 0.524
nipa1
NIPA magnesium transporter 1.
      
 0.518
Lyrm4
Si:ch211-152c8.4; Belongs to the complex I LYR family.
      
 0.515
dera
Deoxyribose-phosphate aldolase (putative).
      
 0.510
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.