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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccne1Cyclin E1; Belongs to the cyclin family. (412 aa)    
Predicted Functional Partners:
cdk2
Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily.
   
 0.992
Rb1
Retinoblastoma 1.
   
 0.984
rbl1
Retinoblastoma-like 1 (p107).
   
 0.982
rbl2
Retinoblastoma-like 2 (p130).
   
 0.982
cdkn1a
Cyclin-dependent kinase inhibitor 1A.
   
 0.979
cdkn1b
Cyclin-dependent kinase inhibitor 1Bb.
   
 0.977
ENSAMXP00000032670
Cyclin-dependent kinase inhibitor 1Ca.
   
 0.977
LOC103041774
Cyclin-dependent kinase inhibitor 1D.
   
 0.977
LOC103030485
Cyclin-dependent kinase inhibitor 1Ba.
   
 0.977
LOC103033872
Cyclin-dependent kinase inhibitor 1Cb.
   
 0.977
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.