Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sec23aProtein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (765 aa)    
Predicted Functional Partners:
sec13
SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.
   
 0.998
W5K202_ASTMX
SEC31 homolog A, COPII coat complex component.
   
 0.995
LOC103026503
SEC31 homolog B, COPII coat complex component.
   
 0.995
sec24d
SEC24 homolog D, COPII coat complex component.
   
0.992
sec24c
SEC24 homolog C, COPII coat complex component.
   
0.991
LOC103039156
SEC24 homolog B, COPII coat complex component.
   
0.980
LOC103040517
SEC24 homolog A, COPII coat complex component.
   
0.980
LOC103039977
Si:dkey-13n15.2.
   
 0.932
Sar1b
Secretion associated, Ras related GTPase 1B.
    
 0.904
ENSAMXP00000045387
Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family.
    
 0.904
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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